Gene name
ADAM10 (Kuz,Madm)
Experiment(s)
For this entry:
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 19 | Signal peptide |
20 | 674 | Extracellular |
675 | 697 | Membrane |
698 | 749 | Cytoplasmic |
Eukaryotic Linear Motif (ELM)
Start | End | Sequence | Motif |
---|---|---|---|
722 | 725 | KRRR | TRG_ER_diArg_1 |
746 | 749 | HMRR | TRG_ER_diArg_1 |
Phosphorylation
Glycosylation
Position | Site resource | Glycan resource | PubMed link(s) |
---|---|---|---|
268 | Glyconnect | 30899004 | |
279 | Glyconnect | 30899004 | |
279 | Glyconnect | 30899004 | |
279 | Glyconnect | 30899004 | |
279 | Glyconnect | 30899004 | |
279 | dbPTM | 19349973 | |
279 | UniProtKB | 19349973 | |
440 | Glyconnect | 30899004 | |
552 | Glyconnect | 30899004 |
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | ADAM10_ADAM17 |
InterPro | ADAM_10 |
InterPro | Disintegrin_dom |
InterPro | Disintegrin_dom_sf |
InterPro | MetalloPept_cat_dom_sf |
InterPro | Peptidase_M12B |
InterPro | Peptidase_M12B_N |
Pfam | Disintegrin |
Pfam | Pep_M12B_propep |