Gene name

ADAM10 (Kuz,Madm)

Experiment(s)

For this entry:
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 19 Signal peptide
20 674 Extracellular
675 697 Membrane
698 749 Cytoplasmic
Eukaryotic Linear Motif (ELM)
Start End Sequence Motif
722 725 KRRR TRG_ER_diArg_1
746 749 HMRR TRG_ER_diArg_1
Phosphorylation
Position Resource
437 4697183
720 4697188
741 15401990
Glycosylation

Family and domain data

Database Domain/Family name
InterPro ADAM10_ADAM17
InterPro ADAM_10
InterPro Disintegrin_dom
InterPro Disintegrin_dom_sf
InterPro MetalloPept_cat_dom_sf
InterPro Peptidase_M12B
InterPro Peptidase_M12B_N
Pfam Disintegrin
Pfam Pep_M12B_propep

By using PolarProtDb you accept the Privacy Notice in compliance with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018. Read the Privacy Notice