Gene name
ITGB1 (FNRB,MDF2,MSK12)
Experiment(s)
For this entry:
A0A5F4CIL4_CANLF (ITGB1)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Tan B,Yatim SMJM,Peng S,Gunaratne J,Hunziker W,Ludwig A (2020) The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions., Curr Biol, 30, 2791-2804.e6. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 23 | Signal peptide |
| 24 | 734 | Extracellular |
| 735 | 750 | Membrane |
| 751 | 801 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | EGF_extracell |
| InterPro | I-EGF_1 |
| InterPro | Integrin_beta-1 |
| InterPro | Integrin_beta_N |
| InterPro | Integrin_bsu |
| InterPro | Integrin_bsu_cyt_dom |
| InterPro | Integrin_bsu_tail |
| InterPro | Integrin_bsu_tail_dom_sf |
| InterPro | Integrin_bsu_VWA |
| InterPro | Integrin_dom_sf |
| InterPro | PSI |
| InterPro | vWFA_dom_sf |
| Pfam | EGF_2 |
| Pfam | I-EGF_1 |
| Pfam | Integrin_b_cyt |
| Pfam | Integrin_B_tail |
| Pfam | Integrin_beta |
| Pfam | PSI_integrin |