Gene name

ANO1 (DOG1,ORAOV2,TAOS2,TMEM16A)

Experiment(s)

For this entry:
A0A0G2K052_RAT (ANO1)
Species Rattus norvegicus
Localization Apical plasma membrane
Reference Silveira JC,Kopp PA (2015) Pendrin and anoctamin as mediators of apical iodide efflux in thyroid cells., Curr Opin Endocrinol Diabetes Obes, 22, 374-80.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Thyroid gland
Cell Follicular cells
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 353 Cytoplasmic
354 376 Membrane
377 429 Extracellular
430 448 Membrane
449 512 Cytoplasmic
513 535 Membrane
536 558 Extracellular
559 579 Membrane
580 605 Cytoplasmic
606 625 Membrane
626 728 Extracellular
729 751 Membrane
752 781 Cytoplasmic
782 803 Membrane
804 880 Extracellular
881 900 Membrane
901 982 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro Anoct_dimer
InterPro Anoctamin
InterPro Anoctamin-1
Pfam Anoct_dimer
Pfam Anoctamin

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