Gene name
SLC30A5 (Slc30a5_predicted,ZNT5,ZNTL1,ZTL1)
Experiment(s)
For this entry:
ZNT5_HUMAN (SLC30A5)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Cragg RA,Christie GR,Phillips SR,Russi RM,Küry S,Mathers JC,Taylor PM,Ford D (2002) A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane., J Biol Chem, 277, 22789-97. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Large intestine |
| Cell | CACO-2 cells (enterocytes) |
| Notes | A Myc-tag was used for labelling |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 31 | Cytoplasmic |
| 32 | 47 | Membrane |
| 48 | 56 | Extracellular |
| 57 | 76 | Membrane |
| 77 | 97 | Cytoplasmic |
| 98 | 116 | Membrane |
| 117 | 121 | Extracellular |
| 122 | 141 | Membrane |
| 142 | 151 | Cytoplasmic |
| 152 | 167 | Membrane |
| 168 | 196 | Extracellular |
| 197 | 216 | Membrane |
| 217 | 238 | Cytoplasmic |
| 239 | 258 | Membrane |
| 259 | 267 | Extracellular |
| 268 | 287 | Membrane |
| 288 | 304 | Cytoplasmic |
| 305 | 320 | Membrane |
| 321 | 342 | Extracellular |
| 343 | 362 | Membrane |
| 363 | 419 | Cytoplasmic |
| 420 | 439 | Membrane |
| 440 | 448 | Extracellular |
| 449 | 468 | Membrane |
| 469 | 485 | Cytoplasmic |
| 486 | 505 | Membrane |
| 506 | 521 | Extracellular |
| 522 | 540 | Membrane |
| 541 | 591 | Cytoplasmic |
| 592 | 613 | Membrane |
| 614 | 622 | Extracellular |
| 623 | 641 | Membrane |
| 642 | 765 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Cation_efflux |
| InterPro | Cation_efflux_TMD_sf |
| Pfam | Cation_efflux |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| TM216_HUMAN | 2 | 26638075 |
| TMM17_HUMAN | 2 | 26638075 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.