Gene name
SLC7A7
Experiment(s)
For this entry:
YLAT1_HUMAN (SLC7A7)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Thul PJ,Åkesson L,Wiking M,Mahdessian D,Geladaki A,Ait Blal H,Alm T,Asplund A,Björk L,Breckels LM,Bäckström A,Danielsson F,Fagerberg L,Fall J,Gatto L,Gnann C,Hober S,Hjelmare M,Johansson F,Lee S,Lindskog C,Mulder J,Mulvey CM,Nilsson P,Oksvold P,Rockberg J,Schutten R,Schwenk JM,Sivertsson Å,Sjöstedt E,Skogs M,Stadler C,Sullivan DP,Tegel H,Winsnes C,Zhang C,Zwahlen M,Mardinoglu A,Pontén F,von Feilitzen K,Lilley KS,Uhlén M,Lundberg E (2017) A subcellular map of the human proteome., Science, 356, . [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes | The antibody HPA036227 was used to detect SLC7A7 in kidney (also in the tissue atlas) |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 36 | Cytoplasmic |
| 37 | 57 | Membrane |
| 58 | 70 | Extracellular |
| 71 | 91 | Membrane |
| 92 | 113 | Cytoplasmic |
| 114 | 135 | Membrane |
| 136 | 156 | Extracellular |
| 157 | 177 | Membrane |
| 178 | 186 | Cytoplasmic |
| 187 | 206 | Membrane |
| 207 | 224 | Extracellular |
| 225 | 245 | Membrane |
| 246 | 261 | Cytoplasmic |
| 262 | 282 | Membrane |
| 283 | 303 | Extracellular |
| 304 | 329 | Membrane |
| 330 | 356 | Cytoplasmic |
| 357 | 376 | Membrane |
| 377 | 383 | Extracellular |
| 384 | 403 | Membrane |
| 404 | 416 | Cytoplasmic |
| 417 | 437 | Membrane |
| 438 | 442 | Extracellular |
| 443 | 463 | Membrane |
| 464 | 511 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 339 | 27462623 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AA/rel_permease1 |
| Pfam | AA_permease_2 |