Gene name

Wnt5a (Wnt-5a)

Experiment(s)

For this entry:
WNT5A_MOUSE (Wnt5a)
Species Mus musculus
Localization Basolateral plasma membrane
Reference Yamamoto H,Awada C,Matsumoto S,Kaneiwa T,Sugimoto T,Takao T,Kikuchi A (2015) Basolateral secretion of Wnt5a in polarized epithelial cells is required for apical lumen formation., J Cell Sci, 128, 1051-63.
[PubMed] [DOI]
Evidence level Selective medium analysis
Organ Kidney
Cell MDCK cells (distal tubule)
Notes When extra N-glycosylation regions were added
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 380 Extracellular
Glycosylation

Family and domain data

Database Domain/Family name
InterPro Wnt
InterPro Wnt5a
InterPro Wnt_C
InterPro Wnt_CS
Pfam wnt

Interactions

With (links to EBI) #Exp PubMed links
KLOT_MOUSE 2 17690294
Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.

By using PolarProtDb you accept the Privacy Notice in compliance with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018. Read the Privacy Notice