Gene name
Wnt3a (Wnt-3a)
Experiment(s)
For this entry:
WNT3A_MOUSE (Wnt3a)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Yamamoto H,Awada C,Hanaki H,Sakane H,Tsujimoto I,Takahashi Y,Takao T,Kikuchi A (2013) The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by different mechanisms., J Cell Sci, 126, 2931-43. [PubMed] [DOI] |
| Evidence level | Selective medium analysis |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | The amoung of secreted protein per medium was quantified by western blots. N-glycosylation directed sorting |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 352 | Extracellular |
Family and domain data
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| TIKI2_HUMAN | 2 | 22726442 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.