Gene name
Trpv2 (Grc,VRL)
Experiment(s)
For this entry:
TRPV2_MOUSE (Trpv2)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Yu W,Hill WG,Apodaca G,Zeidel ML (2011) Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium., Am J Physiol Renal Physiol, 300, F49-59. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Bladder |
| Cell | Urothelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 387 | Cytoplasmic |
| 388 | 407 | Membrane |
| 408 | 428 | Extracellular |
| 429 | 452 | Membrane |
| 453 | 468 | Cytoplasmic |
| 469 | 487 | Membrane |
| 488 | 492 | Extracellular |
| 493 | 511 | Membrane |
| 512 | 522 | Cytoplasmic |
| 523 | 550 | Membrane |
| 551 | 588 | Extracellular |
| 589 | 605 | Re-entrant loop |
| 606 | 615 | Extracellular |
| 616 | 639 | Membrane |
| 640 | 756 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ankyrin_rpt |
| InterPro | Ankyrin_rpt-contain_dom |
| InterPro | Ankyrin_rpt-contain_sf |
| InterPro | Ion_trans_dom |
| InterPro | TRPV |
| InterPro | TRPV1-4_channel |
| InterPro | TRPV2_channel |
| Pfam | Ank_2 |
| Pfam | Ion_trans |