Gene name
TRPC4 (Trpc4_v2,Trrp4)
Experiment(s)
For this entry:
TRPC4_MOUSE (TRPC4)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Yu W,Hill WG,Apodaca G,Zeidel ML (2011) Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium., Am J Physiol Renal Physiol, 300, F49-59. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Bladder |
| Cell | Urothelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 329 | Cytoplasmic |
| 330 | 349 | Membrane |
| 350 | 400 | Extracellular |
| 401 | 416 | Membrane |
| 417 | 435 | Cytoplasmic |
| 436 | 455 | Membrane |
| 456 | 475 | Extracellular |
| 476 | 498 | Membrane |
| 499 | 518 | Cytoplasmic |
| 519 | 534 | Membrane |
| 535 | 567 | Extracellular |
| 568 | 583 | Membrane |
| 584 | 595 | Cytoplasmic |
| 596 | 618 | Membrane |
| 619 | 654 | Extracellular |
| 655 | 670 | Membrane |
| 671 | 974 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ankyrin_rpt |
| InterPro | Ankyrin_rpt-contain_dom |
| InterPro | Ankyrin_rpt-contain_sf |
| InterPro | Ion_trans_dom |
| InterPro | TRP_dom |
| InterPro | TRPC4_channel |
| InterPro | TRPC_channel |
| Pfam | Ion_trans |
| Pfam | TRP_2 |