Gene name
Trpc1 (TRP1,Trrp1)
Experiment(s)
For this entry:
TRPC1_MOUSE (Trpc1)
| Species | Mus musculus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Yu W,Hill WG,Apodaca G,Zeidel ML (2011) Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium., Am J Physiol Renal Physiol, 300, F49-59. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Bladder |
| Cell | Urothelial cells |
| Notes |
TRPC1_MOUSE (Trpc1)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Pani B,Liu X,Bollimuntha S,Cheng KT,Niesman IR,Zheng C,Achen VR,Patel HH,Ambudkar IS,Singh BB (2013) Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1., J Cell Sci, 126, 667-75. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Salivary gland |
| Cell | Acinar cells |
| Notes | Localization depended on caveolin 1 |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 350 | Cytoplasmic |
| 351 | 371 | Membrane |
| 372 | 386 | Extracellular |
| 387 | 407 | Membrane |
| 408 | 419 | Cytoplasmic |
| 420 | 439 | Membrane |
| 440 | 456 | Extracellular |
| 457 | 476 | Membrane |
| 477 | 496 | Cytoplasmic |
| 497 | 517 | Membrane |
| 518 | 539 | Extracellular |
| 540 | 559 | Membrane |
| 560 | 586 | Cytoplasmic |
| 587 | 607 | Membrane |
| 608 | 622 | Extracellular |
| 623 | 643 | Membrane |
| 644 | 793 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 396 | 25757280 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ankyrin_rpt |
| InterPro | Ankyrin_rpt-contain_sf |
| InterPro | Ion_trans_dom |
| InterPro | TRP_dom |
| InterPro | TRPC1_channel |
| InterPro | TRPC_channel |
| Pfam | Ion_trans |
| Pfam | TRP_2 |