Gene name
SLCO4A1 (OATP4A1,OATPE,SLC21A12,OATP1)
Experiment(s)
For this entry:
SO4A1_HUMAN (SLCO4A1)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Sato K,Sugawara J,Sato T,Mizutamari H,Suzuki T,Ito A,Mikkaichi T,Onogawa T,Tanemoto M,Unno M,Abe T,Okamura K (2003) Expression of organic anion transporting polypeptide E (OATP-E) in human placenta., Placenta, 24, 144-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Placenta |
| Cell | Trophoblast cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 103 | Cytoplasmic |
| 104 | 124 | Membrane |
| 125 | 142 | Extracellular |
| 143 | 164 | Membrane |
| 165 | 171 | Cytoplasmic |
| 172 | 193 | Membrane |
| 194 | 228 | Extracellular |
| 229 | 250 | Membrane |
| 251 | 263 | Cytoplasmic |
| 264 | 285 | Membrane |
| 286 | 308 | Extracellular |
| 309 | 330 | Membrane |
| 331 | 382 | Cytoplasmic |
| 383 | 404 | Membrane |
| 405 | 422 | Extracellular |
| 423 | 444 | Membrane |
| 445 | 453 | Cytoplasmic |
| 454 | 474 | Membrane |
| 475 | 578 | Extracellular |
| 579 | 602 | Membrane |
| 603 | 614 | Cytoplasmic |
| 615 | 638 | Membrane |
| 639 | 666 | Extracellular |
| 667 | 689 | Membrane |
| 690 | 722 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 557 | N-GlycoSiteAtlas | 24190977 | |
| 557 | PolarProtDb | 31844046 | |
| 557 | UniPep |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Kazal_dom |
| InterPro | Kazal_dom_sf |
| InterPro | MFS_dom |
| InterPro | MFS_trans_sf |
| InterPro | OATP |
| Pfam | Kazal_2 |
| Pfam | OATP |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| GPR25_HUMAN | 3 | 32296183 |
| TMM17_HUMAN | 2 | 26638075 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.