Gene name
Slco1c1 (Bsat1,Oatp1c1,Oatpf,Slc21a14,OATP14)
Experiment(s)
For this entry:
SO1C1_RAT (Slco1c1)
| Species | Rattus norvegicus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Roberts LM,Woodford K,Zhou M,Black DS,Haggerty JE,Tate EH,Grindstaff KK,Mengesha W,Raman C,Zerangue N (2008) Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier., Endocrinology, 149, 6251-61. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Vessels |
| Cell | Brain capillary endothelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 43 | Cytoplasmic |
| 44 | 63 | Membrane |
| 64 | 79 | Extracellular |
| 80 | 103 | Membrane |
| 104 | 110 | Cytoplasmic |
| 111 | 132 | Membrane |
| 133 | 189 | Extracellular |
| 190 | 205 | Membrane |
| 206 | 225 | Cytoplasmic |
| 226 | 248 | Membrane |
| 249 | 274 | Extracellular |
| 275 | 297 | Membrane |
| 298 | 357 | Cytoplasmic |
| 358 | 379 | Membrane |
| 380 | 396 | Extracellular |
| 397 | 418 | Membrane |
| 419 | 427 | Cytoplasmic |
| 428 | 449 | Membrane |
| 450 | 557 | Extracellular |
| 558 | 581 | Membrane |
| 582 | 593 | Cytoplasmic |
| 594 | 615 | Membrane |
| 616 | 644 | Extracellular |
| 645 | 668 | Membrane |
| 669 | 716 | Cytoplasmic |
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Kazal_dom |
| InterPro | Kazal_dom_sf |
| InterPro | MFS_dom |
| InterPro | MFS_trans_sf |
| InterPro | OATP |
| InterPro | OATP1C1 |
| Pfam | Kazal_2 |
| Pfam | OATP |