Gene name
SLCO1B3 (LST2,OATP1B3,OATP8,SLC21A8)
Experiment(s)
For this entry:
SO1B3_HUMAN (SLCO1B3)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
König J,Cui Y,Nies AT,Keppler D (2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide., J Biol Chem, 275, 23161-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
SO1B3_HUMAN (SLCO1B3)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
König J,Cui Y,Nies AT,Keppler D (2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide., J Biol Chem, 275, 23161-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
SO1B3_HUMAN (SLCO1B3)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
König J,Cui Y,Nies AT,Keppler D (2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide., J Biol Chem, 275, 23161-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Loading data
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 26 | Cytoplasmic |
| 27 | 48 | Membrane |
| 49 | 64 | Extracellular |
| 65 | 86 | Membrane |
| 87 | 95 | Cytoplasmic |
| 96 | 117 | Membrane |
| 118 | 171 | Extracellular |
| 172 | 193 | Membrane |
| 194 | 206 | Cytoplasmic |
| 207 | 230 | Membrane |
| 231 | 254 | Extracellular |
| 255 | 278 | Membrane |
| 279 | 336 | Cytoplasmic |
| 337 | 358 | Membrane |
| 359 | 375 | Extracellular |
| 376 | 397 | Membrane |
| 398 | 406 | Cytoplasmic |
| 407 | 428 | Membrane |
| 429 | 536 | Extracellular |
| 537 | 559 | Membrane |
| 560 | 572 | Cytoplasmic |
| 573 | 594 | Membrane |
| 595 | 624 | Extracellular |
| 625 | 647 | Membrane |
| 648 | 702 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 134 | N-GlycoSiteAtlas | 24495048 | |
| 145 | N-GlycoSiteAtlas | 24495048 | |
| 151 | N-GlycoSiteAtlas | 24495048 | |
| 445 | N-GlycoSiteAtlas | 24495048 | |
| 503 | N-GlycoSiteAtlas | 24495048 | |
| 516 | N-GlycoSiteAtlas | 24495048 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Kazal_dom |
| InterPro | Kazal_dom_sf |
| InterPro | MFS_dom |
| InterPro | MFS_trans_sf |
| InterPro | OATP |
| Pfam | Kazal_2 |
| Pfam | OATP |