PolarProtDb

Gene name

SLCO1B3 (LST2,OATP1B3,OATP8,SLC21A8)

Experiment(s)

For this entry:

SO1B3_HUMAN (SLCO1B3)

Species	Homo sapiens
Localization	Basolateral plasma membrane
Reference	König J,Cui Y,Nies AT,Keppler D (2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide., J Biol Chem, 275, 23161-8. [PubMed] [DOI]
Evidence level	Antibody staining
Organ	Kidney
Cell	MDCK cells (distal tubule)
Notes

SO1B3_HUMAN (SLCO1B3)

Species	Homo sapiens
Localization	Basolateral plasma membrane
Reference	König J,Cui Y,Nies AT,Keppler D (2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide., J Biol Chem, 275, 23161-8. [PubMed] [DOI]
Evidence level	Antibody staining
Organ	Liver
Cell	Hepatocytes
Notes

SO1B3_HUMAN (SLCO1B3)

Species	Homo sapiens
Localization	Basolateral plasma membrane
Reference	König J,Cui Y,Nies AT,Keppler D (2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide., J Biol Chem, 275, 23161-8. [PubMed] [DOI]
Evidence level	Antibody staining
Organ	Liver
Cell	Hepatocytes
Notes

For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	26	Cytoplasmic
27	48	Membrane
49	64	Extracellular
65	86	Membrane
87	95	Cytoplasmic
96	117	Membrane
118	171	Extracellular
172	193	Membrane
194	206	Cytoplasmic
207	230	Membrane
231	254	Extracellular
255	278	Membrane
279	336	Cytoplasmic
337	358	Membrane
359	375	Extracellular
376	397	Membrane
398	406	Cytoplasmic
407	428	Membrane
429	536	Extracellular
537	559	Membrane
560	572	Cytoplasmic
573	594	Membrane
595	624	Extracellular
625	647	Membrane
648	702	Cytoplasmic

Phosphorylation

Position	Resource
38	11000753
293	469909
295	469910
312	23146196
537	23146198
559	34350240
598	34349114
603	34349117
604	34349120
606	34349123
642	23051671
667	7999236

Glycosylation

Position	Site resource	PubMed link(s)
134	N-GlycoSiteAtlas	24495048
145	N-GlycoSiteAtlas	24495048
151	N-GlycoSiteAtlas	24495048
445	N-GlycoSiteAtlas	24495048
503	N-GlycoSiteAtlas	24495048
516	N-GlycoSiteAtlas	24495048

Family and domain data

Database	Domain/Family name
InterPro	Kazal_dom
InterPro	Kazal_dom_sf
InterPro	MFS_dom
InterPro	MFS_trans_sf
InterPro	OATP
Pfam	Kazal_2
Pfam	OATP