Gene name
SLCO1B1 (LST1,OATP1B1,OATP2,OATPC,SLC21A6)
Experiment(s)
For this entry:
| Species |
Homo sapiens |
| Localization |
Basolateral plasma membrane |
| Reference |
König J,Cui Y,Nies AT,Keppler D (2000) A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane., Am J Physiol Gastrointest Liver Physiol, 278, G156-64.
[PubMed]
[DOI] |
| Evidence level |
Antibody staining |
| Organ |
Liver |
| Cell |
Hepatocytes |
| Notes |
|
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start |
End |
Localisation |
| 1 |
28 |
Cytoplasmic |
| 29 |
48 |
Membrane |
| 49 |
66 |
Extracellular |
| 67 |
88 |
Membrane |
| 89 |
95 |
Cytoplasmic |
| 96 |
117 |
Membrane |
| 118 |
171 |
Extracellular |
| 172 |
193 |
Membrane |
| 194 |
206 |
Cytoplasmic |
| 207 |
229 |
Membrane |
| 230 |
256 |
Extracellular |
| 257 |
278 |
Membrane |
| 279 |
335 |
Cytoplasmic |
| 336 |
357 |
Membrane |
| 358 |
375 |
Extracellular |
| 376 |
397 |
Membrane |
| 398 |
406 |
Cytoplasmic |
| 407 |
428 |
Membrane |
| 429 |
536 |
Extracellular |
| 537 |
560 |
Membrane |
| 561 |
571 |
Cytoplasmic |
| 572 |
594 |
Membrane |
| 595 |
624 |
Extracellular |
| 625 |
646 |
Membrane |
| 647 |
691 |
Cytoplasmic |
Phosphorylation
Glycosylation
Family and domain data