Gene name
Slco1a4 (Oatp1a4,Oatp2,Slc21a5)
Experiment(s)
For this entry:
SO1A4_RAT (Slco1a4)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Kakyo M,Sakagami H,Nishio T,Nakai D,Nakagomi R,Tokui T,Naitoh T,Matsuno S,Abe T,Yawo H (1999) Immunohistochemical distribution and functional characterization of an organic anion transporting polypeptide 2 (oatp2)., FEBS Lett, 445, 343-6. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Liver |
| Cell | Hepatocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 20 | Cytoplasmic |
| 21 | 41 | Membrane |
| 42 | 57 | Extracellular |
| 58 | 79 | Membrane |
| 80 | 87 | Cytoplasmic |
| 88 | 109 | Membrane |
| 110 | 157 | Extracellular |
| 158 | 179 | Membrane |
| 180 | 192 | Cytoplasmic |
| 193 | 213 | Membrane |
| 214 | 242 | Extracellular |
| 243 | 264 | Membrane |
| 265 | 315 | Cytoplasmic |
| 316 | 337 | Membrane |
| 338 | 353 | Extracellular |
| 354 | 375 | Membrane |
| 376 | 385 | Cytoplasmic |
| 386 | 407 | Membrane |
| 408 | 511 | Extracellular |
| 512 | 535 | Membrane |
| 536 | 547 | Cytoplasmic |
| 548 | 569 | Membrane |
| 570 | 598 | Extracellular |
| 599 | 620 | Membrane |
| 621 | 661 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Kazal_dom |
| InterPro | Kazal_dom_sf |
| InterPro | MFS_dom |
| InterPro | MFS_trans_sf |
| InterPro | OATP |
| Pfam | Kazal_2 |
| Pfam | OATP |