Gene name

Slco1a1 (Oatp1,Oatp1a1,Slc21a1)

Experiment(s)

For this entry:
SO1A1_RAT (Slco1a1)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Bergwerk AJ,Shi X,Ford AC,Kanai N,Jacquemin E,Burk RD,Bai S,Novikoff PM,Stieger B,Meier PJ,Schuster VL,Wolkoff AW (1996) Immunologic distribution of an organic anion transport protein in rat liver and kidney., Am J Physiol, 271, G231-8.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Liver
Cell Hepatocytes
Notes
SO1A1_RAT (Slco1a1)
Species Rattus norvegicus
Localization Apical plasma membrane
Reference Bergwerk AJ,Shi X,Ford AC,Kanai N,Jacquemin E,Burk RD,Bai S,Novikoff PM,Stieger B,Meier PJ,Schuster VL,Wolkoff AW (1996) Immunologic distribution of an organic anion transport protein in rat liver and kidney., Am J Physiol, 271, G231-8.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell Proximal tubules
Notes
SO1A1_RAT (Slco1a1)
Species Rattus norvegicus
Localization Apical plasma membrane
Reference Angeletti RH,Novikoff PM,Juvvadi SR,Fritschy JM,Meier PJ,Wolkoff AW (1997) The choroid plexus epithelium is the site of the organic anion transport protein in the brain., Proc Natl Acad Sci U S A, 94, 283-6.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Choroid plexus
Cell Ependymal cells
Notes
SO1A1_RAT (Slco1a1)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Eckhardt U,Schroeder A,Stieger B,Höchli M,Landmann L,Tynes R,Meier PJ,Hagenbuch B (1999) Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells., Am J Physiol, 276, G1037-42.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Liver
Cell Hepatocytes
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 20 Cytoplasmic
21 41 Membrane
42 57 Extracellular
58 79 Membrane
80 87 Cytoplasmic
88 109 Membrane
110 158 Extracellular
159 180 Membrane
181 195 Cytoplasmic
196 217 Membrane
218 243 Extracellular
244 265 Membrane
266 315 Cytoplasmic
316 337 Membrane
338 353 Extracellular
354 376 Membrane
377 386 Cytoplasmic
387 408 Membrane
409 512 Extracellular
513 535 Membrane
536 548 Cytoplasmic
549 571 Membrane
572 600 Extracellular
601 622 Membrane
623 670 Cytoplasmic
Eukaryotic Linear Motif (ELM)
Start End Sequence Motif
666 670 LKTKL TRG_PTS1
Phosphorylation
Position Resource
634 460719
635 460720
657 33598250
Glycosylation
Position Site resource Glycan resource PubMed link(s)
124 dbPTM 18308854
124 UniProtKB 18308854
135 dbPTM 18308854
135 UniProtKB 18308854
492 dbPTM 18308854
492 UniProtKB 18308854

Family and domain data

Database Domain/Family name
InterPro Kazal_dom
InterPro Kazal_dom_sf
InterPro MFS_dom
InterPro MFS_trans_sf
InterPro OATP
Pfam Kazal_2
Pfam OATP

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