PolarProtDb

Gene name

SCARB1 (Srb1,CD36L1,CLA1)

Experiment(s)

For this entry:

SCRB1_HUMAN (SCARB1)

Species	Homo sapiens
Localization	Apical plasma membrane
Reference	Pshezhetsky AV,Fedjaev M,Ashmarina L,Mazur A,Budman L,Sinnett D,Labuda D,Beaulieu JF,Ménard D,Nifant'ev I,Levy E (2007) Subcellular proteomics of cell differentiation: quantitative analysis of the plasma membrane proteome of Caco-2 cells., Proteomics, 7, 2201-15. [PubMed] [DOI]
Evidence level	Large-scale proteomics
Organ	Large intestine
Cell	CACO-2 cells (enterocytes)
Notes	Cutoff: at least 4-fold enrichment (A/total) at any repetition

For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	11	Cytoplasmic
12	32	Membrane
33	446	Extracellular
447	464	Membrane
465	552	Cytoplasmic

Phosphorylation

Position	Resource
92	55377619
175	23141908

Glycosylation

Position	Site resource	Glycan resource	PubMed link(s)
102	N-GlycoSiteAtlas		24495048
102	PolarProtDb		31844046
102	UniPep
102	UniProtKB		19159218
102	dbPTM		19159218
108	N-GlycoSiteAtlas		24495048
108	PolarProtDb		31844046
108	UniPep
173	N-GlycoSiteAtlas		24495048
212	N-GlycoSiteAtlas		24495048
227	N-GlycoSiteAtlas		21645671 , 24741114 , 24495048
227	PolarProtDb		31844046
227	Glyconnect	$WURCS=2.0/2,10,9/[axxxxh-1x_1-5_2*NCC/3=O][axxxxh-1x_1-5]/1-1-2-2-2-2-2-2-2-2/a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?\|j?$	29741879
255	N-GlycoSiteAtlas		24495048
310	N-GlycoSiteAtlas		24495048
310	UniPep
330	dbPTM		19159218
330	N-GlycoSiteAtlas		24495048
330	UniPep
330	UniProtKB		19159218
369	O-GlycoProteomDB
383	N-GlycoSiteAtlas		24495048

Family and domain data

Database	Domain/Family name
InterPro	CD36/SCARB1/SNMP1
InterPro	CD36_fam
Pfam	CD36

Interactions

With (links to EBI)	#Exp	PubMed links
KRA59_HUMAN	3	25416956
KR109_HUMAN	3	25416956
CD81_HUMAN	3	30024968

Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.