Gene name
SCNN1G
Experiment(s)
For this entry:
SCNNG_HUMAN (SCNN1G)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Hanukoglu I,Boggula VR,Vaknine H,Sharma S,Kleyman T,Hanukoglu A (2017) Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages., Histochem Cell Biol, 147, 733-748. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Sweat glands |
| Cell | Ductal cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 53 | Cytoplasmic |
| 54 | 75 | Membrane |
| 76 | 536 | Extracellular |
| 537 | 558 | Membrane |
| 559 | 649 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ENaC |
| InterPro | ENaC_chordates |
| InterPro | ENaC_CS |
| Pfam | ASC |
Interactions
| With (links to EBI) | #Exp | PubMed links |
|---|---|---|
| SCNNA_HUMAN | 3 | 21775436 , 16423824 |
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.