Gene name
Slc6a19 (B0at1,Xt3)
Experiment(s)
For this entry:
S6A19_MOUSE (Slc6a19)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Danilczyk U,Sarao R,Remy C,Benabbas C,Stange G,Richter A,Arya S,Pospisilik JA,Singer D,Camargo SM,Makrides V,Ramadan T,Verrey F,Wagner CA,Penninger JM (2006) Essential role for collectrin in renal amino acid transport., Nature, 444, 1088-91. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 40 | Cytoplasmic |
| 41 | 62 | Membrane |
| 63 | 67 | Extracellular |
| 68 | 87 | Membrane |
| 88 | 117 | Cytoplasmic |
| 118 | 138 | Membrane |
| 139 | 195 | Extracellular |
| 196 | 213 | Membrane |
| 214 | 218 | Cytoplasmic |
| 219 | 238 | Membrane |
| 239 | 264 | Extracellular |
| 265 | 286 | Membrane |
| 287 | 302 | Cytoplasmic |
| 303 | 320 | Membrane |
| 321 | 418 | Extracellular |
| 419 | 440 | Membrane |
| 441 | 456 | Cytoplasmic |
| 457 | 475 | Membrane |
| 476 | 480 | Extracellular |
| 481 | 502 | Membrane |
| 503 | 532 | Cytoplasmic |
| 533 | 560 | Membrane |
| 561 | 580 | Extracellular |
| 581 | 597 | Membrane |
| 598 | 634 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Na/ntran_symport |
| InterPro | Neutral_aa_SLC6 |
| InterPro | SNS_sf |
| Pfam | SNF |