Gene name
Slc6a18 (Xt2,XTRP2)
Experiment(s)
For this entry:
S6A18_MOUSE (Slc6a18)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Vanslambrouck JM,Bröer A,Thavyogarajah T,Holst J,Bailey CG,Bröer S,Rasko JE (2010) Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria., Biochem J, 428, 397-407. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 25 | Cytoplasmic |
| 26 | 43 | Membrane |
| 44 | 55 | Extracellular |
| 56 | 77 | Membrane |
| 78 | 98 | Cytoplasmic |
| 99 | 120 | Membrane |
| 121 | 177 | Extracellular |
| 178 | 198 | Membrane |
| 199 | 207 | Cytoplasmic |
| 208 | 229 | Membrane |
| 230 | 255 | Extracellular |
| 256 | 277 | Membrane |
| 278 | 287 | Cytoplasmic |
| 288 | 309 | Membrane |
| 310 | 399 | Extracellular |
| 400 | 421 | Membrane |
| 422 | 441 | Cytoplasmic |
| 442 | 463 | Membrane |
| 464 | 473 | Extracellular |
| 474 | 495 | Membrane |
| 496 | 516 | Cytoplasmic |
| 517 | 538 | Membrane |
| 539 | 566 | Extracellular |
| 567 | 588 | Membrane |
| 589 | 615 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | B0AT3_SLC6sbd |
| InterPro | Na/ntran_symport |
| InterPro | Neutral_aa_SLC6 |
| InterPro | SNS_sf |
| Pfam | SNF |