Gene name
SLC52A3 (C20orf54,RFT2,RFVT3,RGD1304644)
Experiment(s)
For this entry:
| Species | Homo sapiens |
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| Localization | Apical plasma membrane |
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| Reference |
Subramanian VS,Rapp L,Marchant JS,Said HM (2011) Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells., Am J Physiol Gastrointest Liver Physiol, 301, G100-9.
[PubMed]
[DOI] |
|---|
| Evidence level | Fluorescent tagging |
|---|
| Organ | Large intestine |
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| Cell | CACO-2 cells (enterocytes) |
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| Notes | |
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For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|
| 1 | 2 | Cytoplasmic |
| 3 | 23 | Membrane |
| 24 | 39 | Extracellular |
| 40 | 60 | Membrane |
| 61 | 72 | Cytoplasmic |
| 73 | 93 | Membrane |
| 94 | 105 | Extracellular |
| 106 | 127 | Membrane |
| 128 | 136 | Cytoplasmic |
| 137 | 157 | Membrane |
| 158 | 220 | Extracellular |
| 221 | 241 | Membrane |
| 242 | 297 | Cytoplasmic |
| 298 | 318 | Membrane |
| 319 | 335 | Extracellular |
| 336 | 356 | Membrane |
| 357 | 359 | Cytoplasmic |
| 360 | 380 | Membrane |
| 381 | 396 | Extracellular |
| 397 | 417 | Membrane |
| 418 | 427 | Cytoplasmic |
| 428 | 448 | Membrane |
| 449 | 469 | Extracellular |
Phosphorylation
Glycosylation
Family and domain data
![WURCS=2.0/2,2,1/[uxxxxh_2*NCC/3=O][uxxxxh]/1-2/a?|b?}-{a?|b?](data:image/png;base64,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)