PolarProtDb

Gene name

SLC52A3 (C20orf54,RFT2,RFVT3,RGD1304644)

Experiment(s)

For this entry:

S52A3_HUMAN (SLC52A3)

Species	Homo sapiens
Localization	Apical plasma membrane
Reference	Subramanian VS,Rapp L,Marchant JS,Said HM (2011) Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells., Am J Physiol Gastrointest Liver Physiol, 301, G100-9. [PubMed] [DOI]
Evidence level	Fluorescent tagging
Organ	Large intestine
Cell	CACO-2 cells (enterocytes)
Notes

For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	2	Cytoplasmic
3	23	Membrane
24	39	Extracellular
40	60	Membrane
61	72	Cytoplasmic
73	93	Membrane
94	105	Extracellular
106	127	Membrane
128	136	Cytoplasmic
137	157	Membrane
158	220	Extracellular
221	241	Membrane
242	297	Cytoplasmic
298	318	Membrane
319	335	Extracellular
336	356	Membrane
357	359	Cytoplasmic
360	380	Membrane
381	396	Extracellular
397	417	Membrane
418	427	Cytoplasmic
428	448	Membrane
449	469	Extracellular

Phosphorylation

Position	Resource
251	4775746

Glycosylation

Position	Site resource	Glycan resource	PubMed link(s)
178	O-GlycoProteomDB
182	UniCarbKB	$WURCS=2.0/2,2,1/[uxxxxh_2*NCC/3=O][uxxxxh]/1-2/a?\|b?}-{a?\|b?$	30459171
182	O-GlycoProteomDB
197	O-GlycoProteomDB

Family and domain data

Database	Domain/Family name
InterPro	Riboflavin_transptr
Pfam	DUF1011