Gene name
SLC47A2 (MATE2)
Experiment(s)
For this entry:
S47A2_HUMAN (SLC47A2)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Masuda S,Terada T,Yonezawa A,Tanihara Y,Kishimoto K,Katsura T,Ogawa O,Inui K (2006) Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2., J Am Soc Nephrol, 17, 2127-35. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
S47A2_HUMAN (SLC47A2)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Motohashi H,Nakao Y,Masuda S,Katsura T,Kamba T,Ogawa O,Inui K (2013) Precise comparison of protein localization among OCT, OAT, and MATE in human kidney., J Pharm Sci, 102, 3302-8. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 32 | Cytoplasmic |
| 33 | 54 | Membrane |
| 55 | 70 | Extracellular |
| 71 | 92 | Membrane |
| 93 | 114 | Cytoplasmic |
| 115 | 136 | Membrane |
| 137 | 152 | Extracellular |
| 153 | 173 | Membrane |
| 174 | 212 | Cytoplasmic |
| 213 | 233 | Membrane |
| 234 | 247 | Extracellular |
| 248 | 269 | Membrane |
| 270 | 290 | Cytoplasmic |
| 291 | 312 | Membrane |
| 313 | 328 | Extracellular |
| 329 | 350 | Membrane |
| 351 | 368 | Cytoplasmic |
| 369 | 389 | Membrane |
| 390 | 409 | Extracellular |
| 410 | 431 | Membrane |
| 432 | 440 | Cytoplasmic |
| 441 | 462 | Membrane |
| 463 | 467 | Extracellular |
| 468 | 489 | Membrane |
| 490 | 578 | Cytoplasmic |
| 579 | 599 | Membrane |
| 600 | 602 | Extracellular |