Gene name
SLC39A12 (Zip12)
Experiment(s)
For this entry:
S39AC_HUMAN (SLC39A12)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Kelleher SL,Velasquez V,Croxford TP,McCormick NH,Lopez V,MacDavid J (2012) Mapping the zinc-transporting system in mammary cells: molecular analysis reveals a phenotype-dependent zinc-transporting network during lactation., J Cell Physiol, 227, 1761-70. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Mammary gland |
| Cell | Acinar cells |
| Notes | Detected in lactating gland |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 24 | Signal peptide |
| 25 | 369 | Extracellular |
| 370 | 390 | Membrane |
| 391 | 399 | Cytoplasmic |
| 400 | 420 | Membrane |
| 421 | 444 | Extracellular |
| 445 | 465 | Membrane |
| 466 | 602 | Cytoplasmic |
| 603 | 623 | Membrane |
| 624 | 630 | Extracellular |
| 631 | 650 | Membrane |
| 651 | 663 | Cytoplasmic |
| 664 | 684 | Membrane |
| 685 | 691 | Extracellular |
Phosphorylation
| Position | Resource |
|---|---|
| 140 | 4154818 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ZIP |
| InterPro | ZIP4_N |
| Pfam | Zip |
| Pfam | ZIP4_domain |