Gene name
SLC39A5 (Slc39a5_predicted,ZIP5)
Experiment(s)
For this entry:
S39A5_MOUSE (SLC39A5)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Wang F,Kim BE,Petris MJ,Eide DJ (2004) The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells., J Biol Chem, 279, 51433-41. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | Overexpressed. HA tag was used for labelling |
S39A5_MOUSE (SLC39A5)
| Species | Mus musculus |
|---|---|
| Localization | Non polar membrane |
| Reference |
Kelleher SL,Velasquez V,Croxford TP,McCormick NH,Lopez V,MacDavid J (2012) Mapping the zinc-transporting system in mammary cells: molecular analysis reveals a phenotype-dependent zinc-transporting network during lactation., J Cell Physiol, 227, 1761-70. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Mammary gland |
| Cell | Acinar cells |
| Notes | Detected in lactating gland |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 24 | Signal peptide |
| 25 | 210 | Extracellular |
| 211 | 232 | Membrane |
| 233 | 242 | Cytoplasmic |
| 243 | 263 | Membrane |
| 264 | 284 | Extracellular |
| 285 | 305 | Membrane |
| 306 | 439 | Cytoplasmic |
| 440 | 461 | Membrane |
| 462 | 470 | Extracellular |
| 471 | 491 | Membrane |
| 492 | 501 | Cytoplasmic |
| 502 | 523 | Membrane |
| 524 | 535 | Extracellular |
Phosphorylation
| Position | Resource |
|---|---|
| 333 | 17546062 |