Gene name
Slc39a4 (Zip4)
Experiment(s)
For this entry:
S39A4_MOUSE (Slc39a4)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Wang F,Kim BE,Petris MJ,Eide DJ (2004) The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells., J Biol Chem, 279, 51433-41. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | Overexpressed. HA tag was used for labelling |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 337 | Extracellular |
| 338 | 359 | Membrane |
| 360 | 368 | Cytoplasmic |
| 369 | 390 | Membrane |
| 391 | 420 | Extracellular |
| 421 | 441 | Membrane |
| 442 | 571 | Cytoplasmic |
| 572 | 592 | Membrane |
| 593 | 599 | Extracellular |
| 600 | 619 | Membrane |
| 620 | 631 | Cytoplasmic |
| 632 | 653 | Membrane |
| 654 | 660 | Extracellular |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | ZIP |
| InterPro | ZIP4_N |
| Pfam | Zip |
| Pfam | ZIP4_domain |