Gene name

Slc39a1 (IRT1,Zip1,Zirtl)

Experiment(s)

For this entry:
S39A1_MOUSE (Slc39a1)
Species Mus musculus
Localization Apical plasma membrane
Reference Kelleher SL,Velasquez V,Croxford TP,McCormick NH,Lopez V,MacDavid J (2012) Mapping the zinc-transporting system in mammary cells: molecular analysis reveals a phenotype-dependent zinc-transporting network during lactation., J Cell Physiol, 227, 1761-70.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Mammary gland
Cell Acinar cells
Notes Detected in lactating gland
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 30 Extracellular
31 51 Membrane
52 68 Cytoplasmic
69 89 Membrane
90 110 Extracellular
111 131 Membrane
132 179 Cytoplasmic
180 199 Membrane
200 209 Extracellular
210 230 Membrane
231 239 Cytoplasmic
240 260 Membrane
261 272 Extracellular
273 292 Membrane
293 302 Cytoplasmic
303 322 Membrane
323 324 Extracellular

Family and domain data

Database Domain/Family name
InterPro ZIP
Pfam Zip

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