Gene name
SLC28A2 (CNT2,Spnt)
Experiment(s)
For this entry:
S28A2_RAT (SLC28A2)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Mangravite LM,Lipschutz JH,Mostov KE,Giacomini KM (2001) Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line., Am J Physiol Renal Physiol, 280, F879-85. [PubMed] [DOI] |
| Evidence level | Fluorescent tagging |
| Organ | Kidney |
| Cell | LLC-PK1 cells (proximal tubule) |
| Notes |
S28A2_RAT (SLC28A2)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Mangravite LM,Lipschutz JH,Mostov KE,Giacomini KM (2001) Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line., Am J Physiol Renal Physiol, 280, F879-85. [PubMed] [DOI] |
| Evidence level | Fluorescent tagging |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | Location was also confirmed by a functional transport assay |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 80 | Cytoplasmic |
| 81 | 100 | Membrane |
| 101 | 104 | Extracellular |
| 105 | 124 | Membrane |
| 125 | 145 | Cytoplasmic |
| 146 | 166 | Membrane |
| 167 | 174 | Extracellular |
| 175 | 191 | Membrane |
| 192 | 201 | Cytoplasmic |
| 202 | 220 | Membrane |
| 221 | 256 | Extracellular |
| 257 | 280 | Membrane |
| 281 | 335 | Cytoplasmic |
| 336 | 356 | Membrane |
| 357 | 360 | Extracellular |
| 361 | 381 | Membrane |
| 382 | 417 | Cytoplasmic |
| 418 | 438 | Membrane |
| 439 | 527 | Extracellular |
| 528 | 551 | Membrane |
| 552 | 567 | Cytoplasmic |
| 568 | 588 | Membrane |
| 589 | 659 | Extracellular |
Phosphorylation
| Position | Resource |
|---|---|
| 46 | 4700175 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | C_nuclsd_transpt |
| InterPro | C_nuclsd_transpt_met_bac |
| InterPro | CNT1/CNT2 |
| InterPro | CNT_C_dom |
| InterPro | CNT_N_dom |
| InterPro | Gate_dom |
| Pfam | Gate |
| Pfam | Nucleos_tra2_C |
| Pfam | Nucleos_tra2_N |