Gene name
Slc26a6 (Cfex,Pat1)
Experiment(s)
For this entry:
S26A6_MOUSE (Slc26a6)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Mukaibo T,Munemasa T,George AT,Tran DT,Gao X,Herche JL,Masaki C,Shull GE,Soleimani M,Melvin JE (2018) The apical anion exchanger Slc26a6 promotes oxalate secretion by murine submandibular gland acinar cells., J Biol Chem, 293, 6259-6268. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Salivary gland |
| Cell | Acinar cells |
| Notes |
S26A6_MOUSE (Slc26a6)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Singh AK,Amlal H,Haas PJ,Dringenberg U,Fussell S,Barone SL,Engelhardt R,Zuo J,Seidler U,Soleimani M (2008) Fructose-induced hypertension: essential role of chloride and fructose absorbing transporters PAT1 and Glut5., Kidney Int, 74, 438-47. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 95 | Cytoplasmic |
| 96 | 116 | Membrane |
| 117 | 121 | Extracellular |
| 122 | 141 | Membrane |
| 142 | 143 | Cytoplasmic |
| 144 | 164 | Membrane |
| 165 | 181 | Extracellular |
| 182 | 209 | Membrane |
| 210 | 214 | Cytoplasmic |
| 215 | 232 | Membrane |
| 233 | 262 | Extracellular |
| 263 | 283 | Membrane |
| 284 | 295 | Cytoplasmic |
| 296 | 313 | Membrane |
| 314 | 343 | Extracellular |
| 344 | 364 | Membrane |
| 365 | 380 | Cytoplasmic |
| 381 | 401 | Membrane |
| 402 | 417 | Extracellular |
| 418 | 438 | Membrane |
| 439 | 443 | Cytoplasmic |
| 444 | 461 | Membrane |
| 462 | 478 | Extracellular |
| 479 | 506 | Membrane |
| 507 | 758 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 751 | 2024805 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | S04_transporter_CS |
| InterPro | SLC26A/SulP_dom |
| InterPro | SLC26A/SulP_fam |
| InterPro | SLC26A6 |
| InterPro | STAS_dom |
| InterPro | STAS_dom_sf |
| Pfam | STAS |
| Pfam | Sulfate_transp |