Gene name
Slc26a1 (Sat1)
Experiment(s)
For this entry:
S26A1_RAT (Slc26a1)
Species | Rattus norvegicus |
---|---|
Localization | Basolateral plasma membrane |
Reference |
Gee HY,Jun I,Braun DA,Lawson JA,Halbritter J,Shril S,Nelson CP,Tan W,Stein D,Wassner AJ,Ferguson MA,Gucev Z,Sayer JA,Milosevic D,Baum M,Tasic V,Lee MG,Hildebrandt F (2016) Mutations in SLC26A1 Cause Nephrolithiasis., Am J Hum Genet, 98, 1228-1234. [PubMed] [DOI] |
Evidence level | Antibody staining |
Organ | Kidney |
Cell | Proximal tubules |
Notes |
S26A1_RAT (Slc26a1)
Species | Rattus norvegicus |
---|---|
Localization | Non polar membrane |
Reference |
Gee HY,Jun I,Braun DA,Lawson JA,Halbritter J,Shril S,Nelson CP,Tan W,Stein D,Wassner AJ,Ferguson MA,Gucev Z,Sayer JA,Milosevic D,Baum M,Tasic V,Lee MG,Hildebrandt F (2016) Mutations in SLC26A1 Cause Nephrolithiasis., Am J Hum Genet, 98, 1228-1234. [PubMed] [DOI] |
Evidence level | Antibody staining |
Organ | Small intestine |
Cell | Enterocytes |
Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 72 | Cytoplasmic |
73 | 93 | Membrane |
94 | 98 | Extracellular |
99 | 118 | Membrane |
119 | 120 | Cytoplasmic |
121 | 140 | Membrane |
141 | 181 | Extracellular |
182 | 202 | Membrane |
203 | 214 | Cytoplasmic |
215 | 232 | Membrane |
233 | 262 | Extracellular |
263 | 280 | Membrane |
281 | 293 | Cytoplasmic |
294 | 313 | Membrane |
314 | 343 | Extracellular |
344 | 364 | Membrane |
365 | 380 | Cytoplasmic |
381 | 401 | Membrane |
402 | 417 | Extracellular |
418 | 438 | Membrane |
439 | 440 | Cytoplasmic |
441 | 459 | Membrane |
460 | 475 | Extracellular |
476 | 503 | Membrane |
504 | 703 | Cytoplasmic |
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | S04_transporter_CS |
InterPro | SLC26A/SulP_dom |
InterPro | SLC26A/SulP_fam |
InterPro | SLC26A1 |
InterPro | STAS_dom |
InterPro | STAS_dom_sf |
Pfam | STAS |
Pfam | Sulfate_transp |