Gene name

Slc26a1 (Sat1)

Experiment(s)

For this entry:
S26A1_RAT (Slc26a1)
Species Rattus norvegicus
Localization Basolateral plasma membrane
Reference Gee HY,Jun I,Braun DA,Lawson JA,Halbritter J,Shril S,Nelson CP,Tan W,Stein D,Wassner AJ,Ferguson MA,Gucev Z,Sayer JA,Milosevic D,Baum M,Tasic V,Lee MG,Hildebrandt F (2016) Mutations in SLC26A1 Cause Nephrolithiasis., Am J Hum Genet, 98, 1228-1234.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Kidney
Cell Proximal tubules
Notes
S26A1_RAT (Slc26a1)
Species Rattus norvegicus
Localization Non polar membrane
Reference Gee HY,Jun I,Braun DA,Lawson JA,Halbritter J,Shril S,Nelson CP,Tan W,Stein D,Wassner AJ,Ferguson MA,Gucev Z,Sayer JA,Milosevic D,Baum M,Tasic V,Lee MG,Hildebrandt F (2016) Mutations in SLC26A1 Cause Nephrolithiasis., Am J Hum Genet, 98, 1228-1234.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Small intestine
Cell Enterocytes
Notes
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 72 Cytoplasmic
73 93 Membrane
94 98 Extracellular
99 118 Membrane
119 120 Cytoplasmic
121 140 Membrane
141 181 Extracellular
182 202 Membrane
203 214 Cytoplasmic
215 232 Membrane
233 262 Extracellular
263 280 Membrane
281 293 Cytoplasmic
294 313 Membrane
314 343 Extracellular
344 364 Membrane
365 380 Cytoplasmic
381 401 Membrane
402 417 Extracellular
418 438 Membrane
439 440 Cytoplasmic
441 459 Membrane
460 475 Extracellular
476 503 Membrane
504 703 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro S04_transporter_CS
InterPro SLC26A/SulP_dom
InterPro SLC26A/SulP_fam
InterPro SLC26A1
InterPro STAS_dom
InterPro STAS_dom_sf
Pfam STAS
Pfam Sulfate_transp

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