Gene name
SLC22A7 (OAT2,NLT)
Experiment(s)
For this entry:
S22A7_MOUSE (SLC22A7)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Ljubojević M,Balen D,Breljak D,Kusan M,Anzai N,Bahn A,Burckhardt G,Sabolić I (2007) Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones., Am J Physiol Renal Physiol, 292, F361-72. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Proximal tubules |
| Notes | Only the S3 segment was expressing this protein |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 20 | Cytoplasmic |
| 21 | 41 | Membrane |
| 42 | 143 | Extracellular |
| 144 | 163 | Membrane |
| 164 | 171 | Cytoplasmic |
| 172 | 192 | Membrane |
| 193 | 197 | Extracellular |
| 198 | 218 | Membrane |
| 219 | 228 | Cytoplasmic |
| 229 | 249 | Membrane |
| 250 | 256 | Extracellular |
| 257 | 276 | Membrane |
| 277 | 343 | Cytoplasmic |
| 344 | 363 | Membrane |
| 364 | 374 | Extracellular |
| 375 | 395 | Membrane |
| 396 | 401 | Cytoplasmic |
| 402 | 422 | Membrane |
| 423 | 429 | Extracellular |
| 430 | 450 | Membrane |
| 451 | 461 | Cytoplasmic |
| 462 | 483 | Membrane |
| 484 | 488 | Extracellular |
| 489 | 510 | Membrane |
| 511 | 540 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 537 | 15503438 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Orgcat_transp/SVOP |
| Pfam | Sugar_tr |