Gene name
UPK1A (TSPAN21)
Experiment(s)
For this entry:
Q06AT5_PIG (UPK1A)
| Species | Sus scrofa |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Višnjar T,Chesi G,Iacobacci S,Polishchuk E,Resnik N,Robenek H,Kreft M,Romih R,Polishchuk R,Kreft ME (2017) Uroplakin traffic through the Golgi apparatus induces its fragmentation: new insights from novel in vitro models., Sci Rep, 7, 12842. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Bladder |
| Cell | Urothelial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 14 | Cytoplasmic |
| 15 | 38 | Membrane |
| 39 | 59 | Extracellular |
| 60 | 82 | Membrane |
| 83 | 90 | Cytoplasmic |
| 91 | 113 | Membrane |
| 114 | 231 | Extracellular |
| 232 | 253 | Membrane |
| 254 | 257 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Tetraspanin |
| InterPro | Tetraspanin/Peripherin |
| InterPro | Tetraspanin_EC2_sf |
| InterPro | Uroplakin-1a |
| Pfam | Tetraspanin |