Gene name
Panx1 (PANX,Px1,MRS1)
Experiment(s)
For this entry:
PANX1_MOUSE (Panx1)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Shum MG,Shao Q,Lajoie P,Laird DW (2019) Destination and consequences of Panx1 and mutant expression in polarized MDCK cells., Exp Cell Res, 381, 235-247. [PubMed] [DOI] |
| Evidence level | Fluorescent tagging |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 36 | Cytoplasmic |
| 37 | 55 | Membrane |
| 56 | 108 | Extracellular |
| 109 | 127 | Membrane |
| 128 | 211 | Cytoplasmic |
| 212 | 233 | Membrane |
| 234 | 273 | Extracellular |
| 274 | 295 | Membrane |
| 296 | 426 | Cytoplasmic |