Gene name

SLC11A2 (Dct1,Dmt1,Nramp2)

Experiment(s)

For this entry:
NRAM2_RAT (SLC11A2)
Species Rattus norvegicus
Localization Apical plasma membrane
Reference Núñez MT,Tapia V,Rojas A,Aguirre P,Gómez F,Nualart F (2010) Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1., Am J Physiol Cell Physiol, 298, C477-85.
[PubMed] [DOI]
Evidence level Antibody staining
Organ Small intestine
Cell Enterocytes
Notes Localization is dynamic
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 66 Cytoplasmic
67 82 Membrane
83 106 Extracellular
107 123 Membrane
124 144 Cytoplasmic
145 169 Membrane
170 182 Extracellular
183 199 Membrane
200 201 Cytoplasmic
202 218 Membrane
219 256 Extracellular
257 273 Membrane
274 294 Cytoplasmic
295 311 Membrane
312 376 Extracellular
377 398 Membrane
399 408 Cytoplasmic
409 425 Membrane
426 439 Extracellular
440 461 Membrane
462 468 Cytoplasmic
469 490 Membrane
491 505 Extracellular
506 527 Membrane
528 568 Cytoplasmic

Family and domain data

Database Domain/Family name
InterPro NRAMP_fam
Pfam Nramp

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