Gene name
SLC11A2 (Dct1,Dmt1,Nramp2)
Experiment(s)
For this entry:
NRAM2_RAT (SLC11A2)
Species | Rattus norvegicus |
---|---|
Localization | Apical plasma membrane |
Reference |
Núñez MT,Tapia V,Rojas A,Aguirre P,Gómez F,Nualart F (2010) Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1., Am J Physiol Cell Physiol, 298, C477-85. [PubMed] [DOI] |
Evidence level | Antibody staining |
Organ | Small intestine |
Cell | Enterocytes |
Notes | Localization is dynamic |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 66 | Cytoplasmic |
67 | 82 | Membrane |
83 | 106 | Extracellular |
107 | 123 | Membrane |
124 | 144 | Cytoplasmic |
145 | 169 | Membrane |
170 | 182 | Extracellular |
183 | 199 | Membrane |
200 | 201 | Cytoplasmic |
202 | 218 | Membrane |
219 | 256 | Extracellular |
257 | 273 | Membrane |
274 | 294 | Cytoplasmic |
295 | 311 | Membrane |
312 | 376 | Extracellular |
377 | 398 | Membrane |
399 | 408 | Cytoplasmic |
409 | 425 | Membrane |
426 | 439 | Extracellular |
440 | 461 | Membrane |
462 | 468 | Cytoplasmic |
469 | 490 | Membrane |
491 | 505 | Extracellular |
506 | 527 | Membrane |
528 | 568 | Cytoplasmic |