Gene name
SLC16A4 (MCT4,Mct5)
Experiment(s)
For this entry:
MOT5_HUMAN (SLC16A4)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Gill RK,Saksena S,Alrefai WA,Sarwar Z,Goldstein JL,Carroll RE,Ramaswamy K,Dudeja PK (2005) Expression and membrane localization of MCT isoforms along the length of the human intestine., Am J Physiol Cell Physiol, 289, C846-52. [PubMed] [DOI] |
| Evidence level | Membrane preparation |
| Organ | Large intestine |
| Cell | Enterocytes |
| Notes |
MOT5_HUMAN (SLC16A4)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Gill RK,Saksena S,Alrefai WA,Sarwar Z,Goldstein JL,Carroll RE,Ramaswamy K,Dudeja PK (2005) Expression and membrane localization of MCT isoforms along the length of the human intestine., Am J Physiol Cell Physiol, 289, C846-52. [PubMed] [DOI] |
| Evidence level | Membrane preparation |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 21 | Cytoplasmic |
| 22 | 43 | Membrane |
| 44 | 59 | Extracellular |
| 60 | 81 | Membrane |
| 82 | 88 | Cytoplasmic |
| 89 | 110 | Membrane |
| 111 | 112 | Extracellular |
| 113 | 134 | Membrane |
| 135 | 144 | Cytoplasmic |
| 145 | 165 | Membrane |
| 166 | 173 | Extracellular |
| 174 | 195 | Membrane |
| 196 | 299 | Cytoplasmic |
| 300 | 320 | Membrane |
| 321 | 336 | Extracellular |
| 337 | 358 | Membrane |
| 359 | 367 | Cytoplasmic |
| 368 | 386 | Membrane |
| 387 | 391 | Extracellular |
| 392 | 413 | Membrane |
| 414 | 425 | Cytoplasmic |
| 426 | 447 | Membrane |
| 448 | 456 | Extracellular |
| 457 | 478 | Membrane |
| 479 | 487 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS |
| InterPro | MFS_dom |
| InterPro | MFS_trans_sf |
| Pfam | MFS_1 |