Gene name
MET
Experiment(s)
For this entry:
MET_HUMAN (MET)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Lung |
| Cell | Airway epithel cells |
| Notes | Only mock-transfected cells were considered |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 24 | Signal peptide |
| 25 | 932 | Extracellular |
| 933 | 954 | Membrane |
| 955 | 1390 | Cytoplasmic |
Phosphorylation
| Position | Resource |
|---|---|
| 17 | 25299993 |
| 468 | 41286696 |
| 637 | 23125383 |
| 641 | 23125386 |
| 745 | 27908514 |
| 750 | 27908517 |
| 755 | 34352232 |
| 758 | 34352235 |
| 759 | 34352238 |
| 830 | 455188 |
| 966 | 4270411 |
| 971 | 23125395 |
| 977 | 2192573 |
| 985 | 450188 |
| 988 | 2192567 |
| 990 | 2192570 |
| 992 | 2428909 |
| 993 | 3180324 |
| 997 | 465844 |
| 1000 | 465843 |
| 1003 | 448469 |
| 1006 | 15421363 |
| 1015 | 40589000 |
| 1016 | 4954979 |
| 1020 | 4956074 |
| 1026 | 15229711 |
| 1093 | 477074 |
| 1096 | 23125389 |
| 1159 | 15229714 |
| 1194 | 473312 |
| 1230 | 448866 |
| 1234 | 448470 |
| 1235 | 448471 |
| 1236 | 2408901 |
| 1241 | 4251180 |
| 1289 | 7445044 |
| 1307 | 23125392 |
| 1313 | 450189 |
| 1342 | 15421366 |
| 1343 | 15412185 |
| 1349 | 448472 |
| 1355 | 2424927 |
| 1356 | 448473 |
| 1365 | 448474 |
| 1367 | 15421369 |
| 1370 | 23125377 |
| 1371 | 23125380 |
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ig-like_fold |
| InterPro | Ig_E-set |
| InterPro | IPT_dom |
| InterPro | Kinase-like_dom_sf |
| InterPro | Plexin |
| InterPro | Plexin_repeat |
| InterPro | Prot_kinase_dom |
| InterPro | Protein_kinase_ATP_BS |
| InterPro | PSI |
| InterPro | Semap_dom |
| InterPro | Semap_dom_sf |
| InterPro | Ser-Thr/Tyr_kinase_cat_dom |
| InterPro | Tyr_kinase_AS |
| InterPro | Tyr_kinase_cat_dom |
| InterPro | Tyr_kinase_HGF/MSP_rcpt |
| InterPro | WD40/YVTN_repeat-like_dom_sf |
| Pfam | PK_Tyr_Ser-Thr |
| Pfam | PSI |
| Pfam | Sema |
| Pfam | TIG |
Interactions
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.