Gene name
MET
Experiment(s)
For this entry:
MET_HUMAN (MET)
Species | Homo sapiens |
---|---|
Localization | Basolateral plasma membrane |
Reference |
Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807. [PubMed] [DOI] |
Evidence level | Large-scale proteomics |
Organ | Lung |
Cell | Airway epithel cells |
Notes | Only mock-transfected cells were considered |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 24 | Signal peptide |
25 | 932 | Extracellular |
933 | 954 | Membrane |
955 | 1390 | Cytoplasmic |
Phosphorylation
Position | Resource |
---|---|
17 | 25299993 |
468 | 41286696 |
637 | 23125383 |
641 | 23125386 |
745 | 27908514 |
750 | 27908517 |
755 | 34352232 |
758 | 34352235 |
759 | 34352238 |
830 | 455188 |
966 | 4270411 |
971 | 23125395 |
977 | 2192573 |
985 | 450188 |
988 | 2192567 |
990 | 2192570 |
992 | 2428909 |
993 | 3180324 |
997 | 465844 |
1000 | 465843 |
1003 | 448469 |
1006 | 15421363 |
1015 | 40589000 |
1016 | 4954979 |
1020 | 4956074 |
1026 | 15229711 |
1093 | 477074 |
1096 | 23125389 |
1159 | 15229714 |
1194 | 473312 |
1230 | 448866 |
1234 | 448470 |
1235 | 448471 |
1236 | 2408901 |
1241 | 4251180 |
1289 | 7445044 |
1307 | 23125392 |
1313 | 450189 |
1342 | 15421366 |
1343 | 15412185 |
1349 | 448472 |
1355 | 2424927 |
1356 | 448473 |
1365 | 448474 |
1367 | 15421369 |
1370 | 23125377 |
1371 | 23125380 |
Glycosylation
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | Ig-like_fold |
InterPro | Ig_E-set |
InterPro | IPT_dom |
InterPro | Kinase-like_dom_sf |
InterPro | Plexin |
InterPro | Plexin_repeat |
InterPro | Prot_kinase_dom |
InterPro | Protein_kinase_ATP_BS |
InterPro | PSI |
InterPro | Semap_dom |
InterPro | Semap_dom_sf |
InterPro | Ser-Thr/Tyr_kinase_cat_dom |
InterPro | Tyr_kinase_AS |
InterPro | Tyr_kinase_cat_dom |
InterPro | Tyr_kinase_HGF/MSP_rcpt |
InterPro | WD40/YVTN_repeat-like_dom_sf |
Pfam | PK_Tyr_Ser-Thr |
Pfam | PSI |
Pfam | Sema |
Pfam | TIG |
Interactions
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.