Gene name
Mal (Mvp17)
Experiment(s)
For this entry:
MAL_HUMAN (Mal)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Martín-Belmonte F,Kremer L,Albar JP,Marazuela M,Alonso MA (1998) Expression of the MAL gene in the thyroid: the MAL proteolipid, a component of glycolipid-enriched membranes, is apically distributed in thyroid follicles., Endocrinology, 139, 2077-84. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Thyroid gland |
| Cell | Follicular cells |
| Notes | Most of the protein is actually in the apical recycling endosome - not on surface |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 21 | Cytoplasmic |
| 22 | 43 | Membrane |
| 44 | 53 | Extracellular |
| 54 | 75 | Membrane |
| 76 | 86 | Cytoplasmic |
| 87 | 108 | Membrane |
| 109 | 125 | Extracellular |
| 126 | 147 | Membrane |
| 148 | 153 | Cytoplasmic |
Family and domain data
Interactions
Protein can be found in apical membrane,
Protein can be found in basal membrane,
Protein can be found both membranes,
Localisation is unknown.