Gene name
LCT (LPH)
Experiment(s)
For this entry:
LPH_HUMAN (LCT)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Delacour D,Cramm-Behrens CI,Drobecq H,Le Bivic A,Naim HY,Jacob R (2006) Requirement for galectin-3 in apical protein sorting., Curr Biol, 16, 408-14. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | A Myc tag was used for labelling |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 20 | Signal peptide |
| 21 | 1881 | Extracellular |
| 1882 | 1901 | Membrane |
| 1902 | 1927 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 1340 | N-GlycoSiteAtlas | ||
| 1340 | UniPep | ||
| 1761 | N-GlycoSiteAtlas | 24741114 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Glyco_hydro_1 |
| InterPro | Glyco_hydro_1_AS |
| InterPro | Glyco_hydro_1_N_CS |
| InterPro | Glycoside_hydrolase_SF |
| Pfam | Glyco_hydro_1 |