Gene name
Lepr (Fa,Obr)
Experiment(s)
For this entry:
LEPR_RAT (Lepr)
| Species | Rattus norvegicus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Buyse M,Berlioz F,Guilmeau S,Tsocas A,Voisin T,Péranzi G,Merlin D,Laburthe M,Lewin MJ,Rozé C,Bado A (2001) PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine., J Clin Invest, 108, 1483-94. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 21 | Signal peptide |
| 22 | 839 | Extracellular |
| 840 | 860 | Membrane |
| 861 | 1162 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | FN3_dom |
| InterPro | FN3_sf |
| InterPro | Hematopoietin_rcpt_Gp130_CS |
| InterPro | Hempt_rcpt_S_F1_CS |
| InterPro | Ig-like_fold |
| InterPro | IgC2-like_lig-bd |
| InterPro | LEP-R_IGD |
| InterPro | Lep_receptor |
| Pfam | Lep_receptor_Ig |
| Pfam | ObR_Ig |