Gene name
SLC7A8 (LAT2,Lat4)
Experiment(s)
For this entry:
LAT2_MOUSE (SLC7A8)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Dave MH,Schulz N,Zecevic M,Wagner CA,Verrey F (2004) Expression of heteromeric amino acid transporters along the murine intestine., J Physiol, 558, 597-610. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
LAT2_MOUSE (SLC7A8)
| Species | Mus musculus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Dave MH,Schulz N,Zecevic M,Wagner CA,Verrey F (2004) Expression of heteromeric amino acid transporters along the murine intestine., J Physiol, 558, 597-610. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Stomach |
| Cell | Parietal cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 38 | Cytoplasmic |
| 39 | 59 | Membrane |
| 60 | 72 | Extracellular |
| 73 | 93 | Membrane |
| 94 | 116 | Cytoplasmic |
| 117 | 138 | Membrane |
| 139 | 158 | Extracellular |
| 159 | 179 | Membrane |
| 180 | 188 | Cytoplasmic |
| 189 | 209 | Membrane |
| 210 | 229 | Extracellular |
| 230 | 250 | Membrane |
| 251 | 268 | Cytoplasmic |
| 269 | 290 | Membrane |
| 291 | 311 | Extracellular |
| 312 | 333 | Membrane |
| 334 | 363 | Cytoplasmic |
| 364 | 381 | Membrane |
| 382 | 388 | Extracellular |
| 389 | 408 | Membrane |
| 409 | 420 | Cytoplasmic |
| 421 | 441 | Membrane |
| 442 | 446 | Extracellular |
| 447 | 467 | Membrane |
| 468 | 531 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | AA/rel_permease1 |
| InterPro | L_AA_transporter |
| Pfam | AA_permease_2 |