Gene name
Kcnj1
Experiment(s)
For this entry:
KCNJ1_MOUSE (Kcnj1)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Estévez R,Boettger T,Stein V,Birkenhäger R,Otto E,Hildebrandt F,Jentsch TJ (2001) Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion., Nature, 414, 558-61. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Henle's loop / TAL cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 59 | Cytoplasmic |
| 60 | 85 | Membrane |
| 86 | 109 | Extracellular |
| 110 | 125 | Re-entrant loop |
| 126 | 134 | Extracellular |
| 135 | 160 | Membrane |
| 161 | 372 | Cytoplasmic |
Phosphorylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ig_E-set |
| InterPro | IRK_C |
| InterPro | K_chnl_inward-rec_Kir |
| InterPro | K_chnl_inward-rec_Kir1.1 |
| InterPro | K_chnl_inward-rec_Kir_cyto |
| InterPro | Kir_TM |
| Pfam | IRK |
| Pfam | IRK_C |