Gene name
KCNJ16
Experiment(s)
For this entry:
KCJ16_HUMAN (KCNJ16)
| Species | Homo sapiens |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Tanemoto M,Abe T,Uchida S,Kawahara K (2014) Mislocalization of K+ channels causes the renal salt wasting in EAST/SeSAME syndrome., FEBS Lett, 588, 899-905. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Distal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 69 | Cytoplasmic |
| 70 | 95 | Membrane |
| 96 | 118 | Extracellular |
| 119 | 135 | Re-entrant loop |
| 136 | 144 | Extracellular |
| 145 | 169 | Membrane |
| 170 | 418 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ig_E-set |
| InterPro | IRK_C |
| InterPro | K_chnl_inward-rec_Kir |
| InterPro | K_chnl_inward-rec_Kir5 |
| InterPro | K_chnl_inward-rec_Kir_cyto |
| InterPro | Kir_TM |
| Pfam | IRK |
| Pfam | IRK_C |