Gene name
IL6 (IFNB2)
Experiment(s)
For this entry:
IL6_BOVIN (IL6)
| Species | Bos taurus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Healy LL,Cronin JG,Sheldon IM (2015) Polarized Epithelial Cells Secrete Interleukin 6 Apically in the Bovine Endometrium., Biol Reprod, 92, 151. [PubMed] [DOI] |
| Evidence level | Selective medium analysis |
| Organ | Uterus |
| Cell | Endometrial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 208 | Extracellular |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | 4_helix_cytokine-like_core |
| InterPro | IL-6 |
| InterPro | IL-6/GCSF/MGF |
| InterPro | IL6/GCSF/MGF_CS |
| Pfam | IL6 |