Gene name
Slc2a12 (Glut12,Slc2a12_predicted)
Experiment(s)
For this entry:
GTR12_HUMAN (Slc2a12)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Linden KC,DeHaan CL,Zhang Y,Glowacka S,Cox AJ,Kelly DJ,Rogers S (2006) Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy., Am J Physiol Renal Physiol, 290, F205-13. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Collecting ducts |
| Notes |
GTR12_HUMAN (Slc2a12)
| Species | Homo sapiens |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Linden KC,DeHaan CL,Zhang Y,Glowacka S,Cox AJ,Kelly DJ,Rogers S (2006) Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy., Am J Physiol Renal Physiol, 290, F205-13. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | Distal tubules |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 38 | Cytoplasmic |
| 39 | 60 | Membrane |
| 61 | 80 | Extracellular |
| 81 | 101 | Membrane |
| 102 | 108 | Cytoplasmic |
| 109 | 130 | Membrane |
| 131 | 133 | Extracellular |
| 134 | 155 | Membrane |
| 156 | 166 | Cytoplasmic |
| 167 | 188 | Membrane |
| 189 | 195 | Extracellular |
| 196 | 217 | Membrane |
| 218 | 278 | Cytoplasmic |
| 279 | 299 | Membrane |
| 300 | 315 | Extracellular |
| 316 | 337 | Membrane |
| 338 | 344 | Cytoplasmic |
| 345 | 366 | Membrane |
| 367 | 461 | Extracellular |
| 462 | 483 | Membrane |
| 484 | 499 | Cytoplasmic |
| 500 | 521 | Membrane |
| 522 | 528 | Extracellular |
| 529 | 549 | Membrane |
| 550 | 617 | Cytoplasmic |
Phosphorylation
Glycosylation
| Position | Site resource | Glycan resource | PubMed link(s) |
|---|---|---|---|
| 383 | N-GlycoSiteAtlas | 24495048 | |
| 383 | PolarProtDb | 31844046 | |
| 396 | PolarProtDb | 31844046 | |
| 432 | PhosphoSitePlus |
![WURCS=2.0/1,1,0/[a2112h-1x_1-5_2*NCC/3=O]/1/](data:image/png;base64,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)
|
|
| 432 | dbPTM | 55834983 | |
| 432 | O-GlycoProteomDB | ||
| 433 | PhosphoSitePlus |
|
|
| 433 | dbPTM | 55834987 | |
| 433 | O-GlycoProteomDB | ||
| 434 | PhosphoSitePlus |
|
|
| 434 | dbPTM | 55834993 | |
| 434 | O-GlycoProteomDB | ||
| 436 | O-GlycoProteomDB | ||
| 445 | PhosphoSitePlus |
|
|
| 445 | dbPTM | 55831495 |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | MFS_dom |
| InterPro | MFS_sugar_transport-like |
| InterPro | MFS_trans_sf |
| InterPro | Sugar/inositol_transpt |
| InterPro | Sugar_transporter_CS |
| Pfam | Sugar_tr |