PolarProtDb

Gene name

GALNT2

Experiment(s)

For this entry:

GALT2_HUMAN (GALNT2)

Species	Homo sapiens
Localization	Non polar membrane
Reference	Touzelet O,Broadbent L,Armstrong SD,Aljabr W,Cloutman-Green E,Power UF,Hiscox JA (2020) The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins., Mol Cell Proteomics, 19, 793-807. [PubMed] [DOI]
Evidence level	Large-scale proteomics
Organ	Lung
Cell	Airway epithel cells
Notes

For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	6	Cytoplasmic
7	24	Membrane
25	571	Extracellular

Phosphorylation

Position	Resource
109	22737302
250	55374581
292	18910520
317	3800274
392	55374585
402	55374587
434	55374589
536	31086506

Glycosylation

Position	Site resource	Glycan resource	PubMed link(s)
59	O-GlycoProteomDB
67	O-GlycoProteomDB
67	dbPTM		55829319
67	PhosphoSitePlus
70	O-GlycoProteomDB
70	dbPTM		55829323
70	PhosphoSitePlus
90	O-GlycoProteomDB
94	O-GlycoProteomDB
109	O-GlycoProteomDB
368	PhosphoSitePlus
368	O-GlycoProteomDB
368	dbPTM		55833067
368	UniCarbKB	$WURCS=2.0/2,2,1/[uxxxxh_2*NCC/3=O][uxxxxh]/1-2/a?\|b?}-{a?\|b?$	30459171
373	O-GlycoProteomDB
375	O-GlycoProteomDB
394	PolarProtDb	$WURCS=2.0/3,3,2/[AUd21122h_5NCC/3=O][uxxxxh_2NCC/3=O][uxxxxh]/1-2-3/a?\|b?\|c?}-{a?\|b?\|c?_a?\|b?\|c?}-{a?\|b?\|c?$	27695962
402	O-GlycoProteomDB
402	PolarProtDb		29296958
402	PolarProtDb		29296958

Family and domain data

Database	Domain/Family name
InterPro	Glyco_trans_2-like
InterPro	Nucleotide-diphossugar_trans
InterPro	Ricin_B-like_lectins
InterPro	Ricin_B_lectin
Pfam	Glycos_transf_2
Pfam	Ricin_B_lectin

Interactions

With (links to EBI)	#Exp	PubMed links
COQ9_HUMAN	3	32296183
KASH5_HUMAN	8	25416956 , 32296183
B2L13_HUMAN	3	32296183
MRM3_HUMAN	3	32296183
TGON2_HUMAN	5	29568061 , 28514442
NOD2_HUMAN	2	21699783

Protein can be found in apical membrane, Protein can be found in basal membrane, Protein can be found both membranes, Localisation is unknown.