Gene name
Fxyd4
Experiment(s)
For this entry:
FXYD4_RAT (Fxyd4)
| Species | Rattus norvegicus |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Lansbery KL,Burcea LC,Mendenhall ML,Mercer RW (2006) Cytoplasmic targeting signals mediate delivery of phospholemman to the plasma membrane., Am J Physiol Cell Physiol, 290, C1275-86. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes | Na+/K+ ATPase is usually basolateral save a few tissues |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 20 | Signal peptide |
| 21 | 35 | Extracellular |
| 36 | 57 | Membrane |
| 58 | 87 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Ion-transport_regulator_FXYD |
| Pfam | ATP1G1_PLM_MAT8 |