Gene name

ERBB3 (HER3)

Experiment(s)

For this entry:
For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start End Localisation
1 20 Signal peptide
21 646 Extracellular
647 664 Membrane
665 1339 Cytoplasmic
Eukaryotic Linear Motif (ELM)
Start End Sequence Motif
1120 1124 SPRPR TRG_ER_diArg_1
Phosphorylation
Glycosylation
Position Site resource Glycan resource PubMed link(s)
250 Glyconnect WURCS=2.0/2,9,8/[axxxxh-1x_1-5_2*NCC/3=O][axxxxh-1x_1-5]/1-1-2-2-2-2-2-2-2/a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i?_a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i?_a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i?_a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i?_a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i?_a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i?_a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i?_a?|b?|c?|d?|e?|f?|g?|h?|i?}-{a?|b?|c?|d?|e?|f?|g?|h?|i? 30899004
250 Glyconnect WURCS=2.0/2,7,6/[axxxxh-1x_1-5_2*NCC/3=O][axxxxh-1x_1-5]/1-1-2-2-2-2-2/a?|b?|c?|d?|e?|f?|g?}-{a?|b?|c?|d?|e?|f?|g?_a?|b?|c?|d?|e?|f?|g?}-{a?|b?|c?|d?|e?|f?|g?_a?|b?|c?|d?|e?|f?|g?}-{a?|b?|c?|d?|e?|f?|g?_a?|b?|c?|d?|e?|f?|g?}-{a?|b?|c?|d?|e?|f?|g?_a?|b?|c?|d?|e?|f?|g?}-{a?|b?|c?|d?|e?|f?|g?_a?|b?|c?|d?|e?|f?|g?}-{a?|b?|c?|d?|e?|f?|g? 30899004
250 Glyconnect WURCS=2.0/2,8,7/[axxxxh-1x_1-5_2*NCC/3=O][axxxxh-1x_1-5]/1-1-2-2-2-2-2-2/a?|b?|c?|d?|e?|f?|g?|h?}-{a?|b?|c?|d?|e?|f?|g?|h?_a?|b?|c?|d?|e?|f?|g?|h?}-{a?|b?|c?|d?|e?|f?|g?|h?_a?|b?|c?|d?|e?|f?|g?|h?}-{a?|b?|c?|d?|e?|f?|g?|h?_a?|b?|c?|d?|e?|f?|g?|h?}-{a?|b?|c?|d?|e?|f?|g?|h?_a?|b?|c?|d?|e?|f?|g?|h?}-{a?|b?|c?|d?|e?|f?|g?|h?_a?|b?|c?|d?|e?|f?|g?|h?}-{a?|b?|c?|d?|e?|f?|g?|h?_a?|b?|c?|d?|e?|f?|g?|h?}-{a?|b?|c?|d?|e?|f?|g?|h? 30899004

Family and domain data

Database Domain/Family name
InterPro Furin-like_Cys-rich_dom
InterPro Furin_repeat
InterPro GF_recep_IV
InterPro Growth_fac_rcpt_cys_sf
InterPro Kinase-like_dom_sf
InterPro Prot_kinase_dom
InterPro Rcpt_L-dom
InterPro Rcpt_L-dom_sf
InterPro Ser-Thr/Tyr_kinase_cat_dom
InterPro Tyr_kinase_AS
InterPro Tyr_kinase_cat_dom
InterPro Tyr_kinase_EGF/ERB/XmrK_rcpt
Pfam Furin-like
Pfam GF_recep_IV
Pfam PK_Tyr_Ser-Thr
Pfam Recep_L_domain

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