Gene name
ERBB3 (HER3)
Experiment(s)
For this entry:
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
Start | End | Localisation |
---|---|---|
1 | 20 | Signal peptide |
21 | 646 | Extracellular |
647 | 664 | Membrane |
665 | 1339 | Cytoplasmic |
Eukaryotic Linear Motif (ELM)
Start | End | Sequence | Motif |
---|---|---|---|
1120 | 1124 | SPRPR | TRG_ER_diArg_1 |
Phosphorylation
Glycosylation
Position | Site resource | Glycan resource | PubMed link(s) |
---|---|---|---|
250 | Glyconnect | 30899004 | |
250 | Glyconnect | 30899004 | |
250 | Glyconnect | 30899004 |
Family and domain data
Database | Domain/Family name |
---|---|
InterPro | Furin-like_Cys-rich_dom |
InterPro | Furin_repeat |
InterPro | GF_recep_IV |
InterPro | Growth_fac_rcpt_cys_sf |
InterPro | Kinase-like_dom_sf |
InterPro | Prot_kinase_dom |
InterPro | Rcpt_L-dom |
InterPro | Rcpt_L-dom_sf |
InterPro | Ser-Thr/Tyr_kinase_cat_dom |
InterPro | Tyr_kinase_AS |
InterPro | Tyr_kinase_cat_dom |
InterPro | Tyr_kinase_EGF/ERB/XmrK_rcpt |
Pfam | Furin-like |
Pfam | GF_recep_IV |
Pfam | PK_Tyr_Ser-Thr |
Pfam | Recep_L_domain |