PolarProtDb

Gene name

ENTPD1 (CD39)

Experiment(s)

For this entry:

ENTP1_HUMAN (ENTPD1)

Species	Homo sapiens
Localization	Apical plasma membrane
Reference	Papanikolaou A,Papafotika A,Murphy C,Papamarcaki T,Tsolas O,Drab M,Kurzchalia TV,Kasper M,Christoforidis S (2005) Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39., J Biol Chem, 280, 26406-14. [PubMed] [DOI]
Evidence level	Antibody staining
Organ	Kidney
Cell	MDCK cells (distal tubule)
Notes

For ortholog entries:

Alignment and sequence features

Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).

CCTOP topology prediction

Start	End	Localisation
1	15	Cytoplasmic
16	37	Membrane
38	477	Extracellular
478	499	Membrane
500	510	Cytoplasmic

Phosphorylation

Position	Resource
49	484673
65	484674

Glycosylation

Position	Site resource	Glycan resource	PubMed link(s)
73	dbPTM		19159218
73	N-GlycoSiteAtlas		19159218
73	UniProtKB		19159218
227	N-GlycoSiteAtlas		24495048
292	dbPTM		19159218
292	N-GlycoSiteAtlas		24190977
292	UniProtKB		19159218
371	Glyconnect	$WURCS=2.0/3,9,8/[Aad21122h-2x_2-6_5NCC/3=O][axxxxh-1x_1-5_2NCC/3=O][axxxxh-1x_1-5]/1-2-2-2-3-3-3-3-3/a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?_a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?}-{a?\|b?\|c?\|d?\|e?\|f?\|g?\|h?\|i?$	29741879
371	N-GlycoSiteAtlas		24741114 , 25247386 , 24495048
457	N-GlycoSiteAtlas		24495048

Family and domain data

Database	Domain/Family name
InterPro	GDA1_CD39_NTPase
Pfam	GDA1_CD39