Gene name
Emp2 (Xmp)
Experiment(s)
For this entry:
EMP2_MOUSE (Emp2)
| Species | Mus musculus |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
Wadehra M,Dayal M,Mainigi M,Ord T,Iyer R,Braun J,Williams CJ (2006) Knockdown of the tetraspan protein epithelial membrane protein-2 inhibits implantation in the mouse., Dev Biol, 292, 430-41. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Uterus |
| Cell | Endometrial cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 1 | Cytoplasmic |
| 2 | 23 | Membrane |
| 24 | 68 | Extracellular |
| 69 | 89 | Membrane |
| 90 | 99 | Cytoplasmic |
| 100 | 121 | Membrane |
| 122 | 145 | Extracellular |
| 146 | 167 | Membrane |
| 168 | 172 | Cytoplasmic |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | EMP-2 |
| InterPro | PMP22/EMP/MP20/Claudin |
| InterPro | PMP22_EMP_MP20 |
| Pfam | PMP22_Claudin |