Gene name
DUOX2 (LNOX2,THOX2)
Experiment(s)
For this entry:
DUOX2_PIG (DUOX2)
| Species | Sus scrofa |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
El Hassani RA,Benfares N,Caillou B,Talbot M,Sabourin JC,Belotte V,Morand S,Gnidehou S,Agnandji D,Ohayon R,Kaniewski J,Noël-Hudson MS,Bidart JM,Schlumberger M,Virion A,Dupuy C (2005) Dual oxidase2 is expressed all along the digestive tract., Am J Physiol Gastrointest Liver Physiol, 288, G933-42. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Large intestine |
| Cell | Enterocytes |
| Notes |
DUOX2_PIG (DUOX2)
| Species | Sus scrofa |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
El Hassani RA,Benfares N,Caillou B,Talbot M,Sabourin JC,Belotte V,Morand S,Gnidehou S,Agnandji D,Ohayon R,Kaniewski J,Noël-Hudson MS,Bidart JM,Schlumberger M,Virion A,Dupuy C (2005) Dual oxidase2 is expressed all along the digestive tract., Am J Physiol Gastrointest Liver Physiol, 288, G933-42. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Small intestine |
| Cell | Enterocytes |
| Notes |
DUOX2_PIG (DUOX2)
| Species | Sus scrofa |
|---|---|
| Localization | Apical plasma membrane |
| Reference |
El Hassani RA,Benfares N,Caillou B,Talbot M,Sabourin JC,Belotte V,Morand S,Gnidehou S,Agnandji D,Ohayon R,Kaniewski J,Noël-Hudson MS,Bidart JM,Schlumberger M,Virion A,Dupuy C (2005) Dual oxidase2 is expressed all along the digestive tract., Am J Physiol Gastrointest Liver Physiol, 288, G933-42. [PubMed] [DOI] |
| Evidence level | Antibody staining |
| Organ | Thyroid gland |
| Cell | Follicular cells |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 26 | Signal peptide |
| 27 | 598 | Extracellular |
| 599 | 620 | Membrane |
| 621 | 1038 | Cytoplasmic |
| 1039 | 1054 | Membrane |
| 1055 | 1077 | Extracellular |
| 1078 | 1099 | Membrane |
| 1100 | 1125 | Cytoplasmic |
| 1126 | 1146 | Membrane |
| 1147 | 1183 | Extracellular |
| 1184 | 1203 | Membrane |
| 1204 | 1216 | Cytoplasmic |
| 1217 | 1237 | Membrane |
| 1238 | 1545 | Extracellular |
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | DUOX2 |
| InterPro | DUOX_peroxidase |
| InterPro | EF-hand-dom_pair |
| InterPro | EF_Hand_1_Ca_BS |
| InterPro | EF_hand_dom |
| InterPro | FAD-bd_8 |
| InterPro | FAD-bd_FR_type |
| InterPro | Fe3_Rdtase_TM_dom |
| InterPro | Fe_red_NAD-bd_6 |
| InterPro | FNR_nucleotide-bd |
| InterPro | Haem_peroxidase_animal |
| InterPro | Haem_peroxidase_sf |
| InterPro | Haem_peroxidase_sf_animal |
| InterPro | Riboflavin_synthase-like_b-brl |
| Pfam | An_peroxidase |
| Pfam | EF-hand_1 |
| Pfam | EF-hand_5 |
| Pfam | FAD_binding_8 |
| Pfam | Ferric_reduct |
| Pfam | NAD_binding_6 |