Gene name
DAG1 (Dag-1)
Experiment(s)
For this entry:
DAG1_CANLF (DAG1)
| Species | Canis lupus familiaris |
|---|---|
| Localization | Basolateral plasma membrane |
| Reference |
Caceres PS,Gravotta D,Zager PJ,Dephoure N,Rodriguez-Boulan E (2019) Quantitative proteomics of MDCK cells identify unrecognized roles of clathrin adaptor AP-1 in polarized distribution of surface proteins., Proc Natl Acad Sci U S A, 116, 11796-11805. [PubMed] [DOI] |
| Evidence level | Large-scale proteomics |
| Organ | Kidney |
| Cell | MDCK cells (distal tubule) |
| Notes |
For ortholog entries:
Alignment and sequence features
Wheel: zoom in/out; drag: scroll left/right. Sequences and features are drawn in three lines. Bottom line: topology (red bar: cytoplasmic region; yellow bar: transmembrane region; transmembrane re-entrant loop; blue bar: extracellular region; black bar: signal peptide). Middle line: amino acid sequence (grey bar or one letter code). Top line: post translational modifications (Y: N-glycosylation site; Y: O-glycosylation site;P: phosphorylation site), intrinsically disordered regions (light green bar: IDR) and short linear motifs (light steel blue bar: ELM region).
CCTOP topology prediction
| Start | End | Localisation |
|---|---|---|
| 1 | 29 | Signal peptide |
| 30 | 749 | Extracellular |
| 750 | 771 | Membrane |
| 772 | 892 | Cytoplasmic |
Glycosylation
Family and domain data
| Database | Domain/Family name |
|---|---|
| InterPro | Alpha-dystroglycan_domain_2 |
| InterPro | Alpha_DG1_N2 |
| InterPro | Cadg |
| InterPro | Cadherin-like_sf |
| InterPro | DAG1_C |
| InterPro | Ig-like_fold |
| InterPro | SEA_DG_dom |
| Pfam | a_DG1_N2 |
| Pfam | DAG1 |